In Drosophila melanogaster, male-biased genes show greater sex-bias in their expression than female-biased genes. For example, when using a fold-change cutoff to classify sex-biased expression, the proportion of male-biased genes to all sex-biased increases as the fold-change cutoff increases. Similarly, when using an FDR of 5% to classify sex-biased genes, the mean sex-bias of male-biased genes (M/F ratio) is much greater than the mean sex-bias of female-biased genes (F/M ratio).

Classification 2-fold 3-fold 5-fold 10-fold
Male 2033 1472 1067 538
Female 2028 693 184 42
Male or Female 4061 2165 1251 580