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In Drosophila melanogaster, male-biased genes show greater sex-bias in their expression than female-biased genes. For example, when using a fold-change cutoff to classify sex-biased expression, the proportion of male-biased genes to all sex-biased increases as the fold-change cutoff increases. Similarly, when using an FDR of 5% to classify sex-biased genes, the mean sex-bias of male-biased genes (M/F ratio) is much greater than the mean sex-bias of female-biased genes (F/M ratio). | ![]() |
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Classification | 2-fold | 3-fold | 5-fold | 10-fold | ![]() |
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Male | 2033 | 1472 | 1067 | 538 | ![]() |
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Female | 2028 | 693 | 184 | 42 | ![]() |
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Male or Female | 4061 | 2165 | 1251 | 580 | ![]() |
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