In D. melanogaster, male-biased genes show a faster rate of molecular evolution than female-biased or unbiased genes (Zhang et al. 2004; Baines et al. 2008). The figures below show the mean ratio of the nonsynonymous and synonymous substitution rates (dN/dS) for genes classified in the Sebida meta-analysis. Comparisons were performed for D. melanogaster vs. D. simulans and D. melanogaster vs. D. yakuba, as well as for the D. melanogaster lineage and. D. melanogaster subgroup. Sex-biased genes were classified using both a FDR of 5% and a 2-fold cutoff.
For a general overview and to compare the four categories (D. melanogaster lineage, D. melanogaster subgroup, D. melanogaster vs. D. simulans and D. melanogaster vs. D. yakuba) we have created the plots below.